"Mouse grimace scale" developed to track pain in lab mice

May 11th, 2010

Tags: mice, nose

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A paper in Nature Methods this week establishes a scale that can estimate how much pain mice are feeling based on facial expressions. The system, called the “mouse grimace scale,” codes movements like squeezing the eyes shut or bulging the nose as indications of pain, similar to those displayed in humans. It’s intended to allow us to study feelings of pain in mice when testing drugs or veterinary procedures. Scientists often use facial expressions in humans as an indication of how much pain they are feeling from electrical shocks, topical acids, and so on; even newborn babies express pain this way

143bdf1136brief.png "Mouse grimace scale" developed to track pain in lab mice

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ArsTechnica

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